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 Teratogens            
  
                                     

Some lab experiments may use chemicals that are considered teratogens. Below is a list of teratogens that are a part of the College of Science's chemical inventory.  If you are pregnant, think you are pregnant or trying to get pregnant, please contact your professor or lab instructor to find out if any of these chemicals may be used in your lab during the semester.

In 1986, California passed Proposition 65, the Safe Drinking Water and Toxic Enforcement Act.  This Proposition shifts the burden of proof in the regulatory process from government to industry. Use of chemicals known to cause cancer or reproductive toxicity is no longer considered "innocent" until proven "guilty" of harming public health by governmental agencies. Identified hazards are placed on a list and automatically become subject to the Act's warning requirements (12 months after listing) and discharge prohibition (20 months after listing). Exemptions from these requirements are allowed only if the business responsible for an exposure or discharge can demonstrate that the amount of chemical in question poses "no significant risk."

bulletTeratogens in the Lab
bulletProposition 65 List  from OEHHA.ORG

 

List of Teratogens

Regulatory Name

Synonyms (Sigma/     Aldrich)

C.A.S. Number

Acetohydroxomic acid

 

546-88-3

Alprazolam

 

28981-97-7

Actinomycin D (98%)

 

50-76-0

Amikacin sulfate

Amikacin: Sulfate ratio 1:2

39831-55-5

Aminoglutethimide

 

125-84-8

Aminoglycosides

 

None listed

Aminopterin

4-Aminofolic acid

54-62-6

Amiodarone Hydrochloride

 

19774-82-4

Anabolic Steroids

(see 1997 Sigma Cat. p1940)

Various

Arsenic Trioxide

Arsenic (III) oxide

1327-53-3

Arsenic Acid, Potassium salt

Potassium Arsenate

7784-41-0

Arsenic Acid, Sodium salt

Sodium Arsenate

10048-95-0

Arsenious Acid, Sodium salt

Sodium m-Arsenite

7784-46-5

Aspirin has warnings about usage during pregnancy)

Acetylsalicylic acid

50-78-2

Atenolol

 

29122-68-7

Azathioprine

 

446-86-6

Barbital

5,5-Diethylbarbituric Acid

57-44-3

Barbital, Sodium salt

Sodium Barbital

144-02-5

Barbituric Acid

2,4,6-Trihydroxypyrimidine

67-52-7

Benomyl

 

17804-35-2

Benzopyrene, 3,4-

Benz[a]pyrene

50-32-8

Benzopyrene, 4,5-

Benz[e]pyrene

192-97-2

Benzphetamine hydrochloride

N-Benzyl-N-alpha-dimethylpenethylamine

5411-22-3

Busulfan

1,4-Butanediol dimethylsulfonate

55-98-1

Butabarbital, Sodium

(Sigma has the free acid only)

143-81-7

Cadmium compounds

(see 1997 Sigma Cat. p1940)

Various

Carbon disulfide

 

75-15-0

Carbon monoxide

 

630-08-0

Carboplatin

cis-Diammine(1,1-cyclobutanedicarboxylato) Platinum

41575-94-4

Chenodiol

Chenodeoxycholic Acid

474-25-9

Chlorambucil

 

305-03-3

Chlorcyclizine hydrochloride

 

1620-21-9

Chlordiazepoxide

(Hydrochloride only-Sigma)

58-25-3

Chlordiazepoxide hydrochloride

 

438-41-5

1-(2-Chloroethyl)-3-cyclohexyl-
1-nitrosourea

Lomustine

13010-47-4

Cladribine

2-Chloro-2'-deoxyadeno- sine

4291-63-8

Clomiphene citrate

 

50-41-9

Cocaine free base

Ecgonine methyl ester benzoate

50-36-2

Cocaine hydrochloride

 

53-21-4

Colchicine

 

Top of Page

Regulatory Name

Synonyms (Sigma/Aldrich)

CAS Number

Cycloheximide

 

66-81-9

Cyclophosphamide (anhyd. & hydrated)

(Sigma offers the monohydrate)

6055-19-2

Cytarabine

Cytosine-beta-D-arabinofuranoside

147-94-4

Danazol

 

17230-88-5

Daunorubicin Hydrochloride

Daunomycin Hydrochloride

23541-50-6

Demechlocycline Hydro- chloride (internal use)

7-Chloro-6-demethyltetracycline hydrochloride

64-73-3

Diazepam

 

439-14-5

1,2-Dibromo-3-chloropropane

 (DBCP)

96-12-8

Dicumarol

3,3'-Methylenebis-(4-hydroxycoumarin)

66-76-2

Diethylstilbesterol

DES

56-53-1

Dihydroergotamine Mesylate

(Methanesulfonate)

6190-39-2

o-Dinitrobenzene

1,2-Dinitrobenzene

528-29-0

m-Dinitrobenzene

1,3-Dinitrobenzene

99-65-0

p-Dinitrobenzene

1,4-Dinitrobenzene

100-25-4

m-Dinitrobenzoic acid

3,4 Dinitrobenzoic Acid

528-45-0

Dinoseb

2-sec-Butyl-4,6-dinitrophenol

88-85-7

5,5-Diphenylhydantoin

Phenytoin free acid

57-41-0

Doxycycline anhydrous, calcium salt & monohydrate (internal use)

(Sigma offers the hydrochloride)

564-25-0    94088-85-4   17086-28-1 

beta-Estradiol

 

50-28-2

Epichlorhydrin

1-Chloro-2,3-epoxypropane

106-89-8

Epinepherine

 

 

Ergotamine Tartrate

 

379-79-3

Estrogens, conjugated

 

12126-59-9

Ethanol in alcoholic beverages

 

64-17-5

Ethionamide

2-Ethyl-4-pyridinecarbothioamide

536-33-4

Ethoxyethanol, 2-

 

110-80-5

Ethoxyethyl acetate, 2-

 

111-15-9

Ethyleneglycol monomethyl ether acetate

 

110-49-6

Ethylene oxide

 

75-21-8

Ethylene thiourea

2-Imidazolidinethione

96-45-7

Etoposide

 

33419-42-0

Fluorouracil

2,4-Dihydroxy-5-fluoropyrimidine

51-21-8

Flurazepam hydrochloride

Flurazepam dihydrochloride

1172-18-5

Flutamide

 

13311-84-7

Fluoxymesterone

9-alpha-Fluoro-11-beta-hydroxy-17-alpha-methyltestosterone

76-43-7

Formamide

 

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Regulatory Name

Synonyms (Sigma/Aldrich)

CAS Number

Halothane

2-Bromo-2-chloro-1,1,1-trifluoroethane

151-67-7

Hexachlorobenzene

 

118-74-1

Hexamethyl phosphoramide

 

680-31-9

Hydroxyurea

 

127-07-1

Iodine-131

 

10043-66-0

Isotretinoin

13-cis-Retinoic Acid

4759-48-2

Lead inorganic compounds (dust)

 

(7439-92-1)

Lithium carbonate

 

554-13-2

Lithium citrate

 

919-16-4

Lorazepam

(+-)-Lorazepam

846-49-1

Mechlorethamine hydrochloride

2-Chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride or Nitrogen Mustard hydrochloride

55-86-7

Medroxyprogesterone acetate

6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate

71-58-9

Megestrol Acetate

 

595-33-5

Melphalan

4-[bis(2-chloroethyl)amino]-L-phenylalanine

148-82-3

Meprobamate

2-Methyl-2-propylpropane-1,3-diolcarbamate

57-53-4

Mercaptopurine

6-Mercaptopurine hydrate

6122-76-1

Mercuric acetate

 

1600-27-7

Mercury inorganic compounds (dust)

 

(7439-97-6)

Methacycline Hydrochloride

 

3963-95-9

Methimazole

 

60-56-0

Methotrexate

(+)-Amethopterin

59-05-2

Methotrexate Sodium

 

15475-56-6

Methoxyethanol, 2-

Ethylene glycol monomethyl ether

109-86-4

Methyl mercury

 

593-74-8

Methyl formamide

 

123-39-7

Mesterone

Methyl testosterone (17-alpha-)

58-18-4

Midizolam (Hydrochloride)

Sigma offers the Maleate 1:1

59467-94-6

Minocycline hydro- chloride (inter'l  use)

 

13614-98-7

Mitoxanthrone Hydrochloride

 

65271-80-9

Oxazepam

 

604-75-1

Oxymetholone

Anasterone

434-07-1

Oxytetracycline (internal  use)

(Sigma offers the dihydrate)

79-57-2      (6153-64-6)

Oxytetracycline Hydro- chloride (internal use)

 

2058-46-0

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Regulatory Name

Synonyms (Sigma/Aldrich)

CAS Number

Neomycin sulfate (internal use)

 

1405-10-3

Netilmicin sulfate

1-N-Ethylsisomicin

56391-57-2

Nickel Carbonyl

 

13463-39-3

Nicotine

(-)-Nicotine free base (natural)

54-11-5

Nitrofurantoin

N-(5-Nitro-2-furylidene)-1-aminohydantoin

67-20-9

Norethisterone

19-Norethindrone

68-22-4

Norethisterone acetate

19-Norethindrone acetate

51-98-9

Norgestrel

D-(-)-Norgestrel

6533-00-2

Paclitaxel

from Taxus brevifolia                      from Taxus yannanensis

33069-62-4

Penicillamine

D-(-)-Penicillamine free base

52-67-5

Pentobarbital, Sodium salt

Sodium pentobarbital

57-33-0

Phenobarbital

 

50-06-6

Phenyl mercuric acetate

 

62-38-4

Phenylmercuric nitrate

 

8003-05-2

Polychlorinated biphenyls (PCB's)

(Sigma offers an EPA Standard)

1336-36-3

Propylthiorouracil

6-n-Propyl-2-thiouracil

51-52-5

Secobarbital, sodium

 

309-43-3

Streptomycin sulfate

 

3810-74-0

Retinol acetate & palmatate (Vitamin A) have warnings about daily internal usage

all-trans-Retinol Acetate and                all-trans-Retinol Palmitate

127-47-9        79-81-2

all-trans-Retinoic Acid

Vitamin A Acid

302-79-4

Tamofixen Citrate

 

54965-24-1

Temazepam

 

846-50-4

Testosterone Enanthate

 

315-37-7

Testosterone (17-beta-) Cipionate

 

58-20-8

Tetracyclines (Internal use)

Tetracycline free base              Tetracycline-Hydrochloride  Tetracycline phosphate complex

60-54-8           64-75-5        1336-20-5

Thalidomide

 

50-35-1

Thioguanine, 6-

2-Amino-6-mercaptopurine

154-42-7

Tobramycin sulfate

 

79645-27-5

Toluene

 

108-88-3

Triazolam

 

28911-01-5

Trypan blue

 

72-57-1

Urethane

Ethyl carbamate

51-79-6

Valproate (Valproic Acid)

2-Propylpentanoic acid

99-66-1

Vinblastine sulfate

 

143-67-9

Vincristine sulfate

 

2068-78-2

Warfarin

3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

81-81-2

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Last modified: June 18, 2009